Introduction: Developmental Delay (DD) refers to a child’s inability to attain developmental milestones compared to healthy peers. Although evidence shows that DD has irreparable impacts on children's lives, several aspects continue to remain unknown.
Objective: This study aimed to investigate the risk factors of DD in children under 5 years old in Tabriz, Iran.
Materials and methods: This case-control study was conducted in 2022 on 150 mothers of children with DD (case group) and 150 mothers of healthy children under five years without DD (control group). The case group was selected via convenience sampling from the Comprehensive Developmental Center in Tabriz. The DD was diagnosed using the Ages and Stages Questionnaires (ASQ). The control group was selected via cluster sampling from the health centers in Tabriz. The data collection tool was a questionnaire measuring sociodemographic/clinical/obstetric/child-related characteristics. In bivariate analysis, independent t-test, chi-square test, and chi-square test for trend (linear-by-linear association) were used. The variables with significant differences were entered into a multivariate logistic regression model (enter method) to find the predictors.
Results: The mean age of mothers was 33.4 ± 6.2 years in the case group and 30.3 ± 5.1 years in the control group. Male children comprised 65.3% of the case group and 52% of the control group. According to the multivariate regression model, mother’s secondary school education or lower (OR= 0.81, 95% CI: 1.25-6.28, P=0.012), history of child hospitalization (OR=3.02, 95% CI: 1.69-5.40, P=0.001), emergency cesarean-section (OR=2.47, 95% CI: 1.10-5.53, P=0.028), maternal infection during pregnancy (OR=5.0, 95% CI;1.48-16.85, P=0.009), and intrauterine growth restriction (OR=3.7, 95% CI; 1.1-12.6, P=0.038) were significantly associated with increased risk of DD; whereas, breastfeeding (OR = 0.49, 95% CI: 0.27-0.87, P=0.016) and male gender (OR=0.53,95% CI: 0.32-0.89, P=0.016) were significantly associated with decreased risk of DD.
Conclusion: Given the risk factors of DD in children under five in Tabriz, targeted developmental screening and early intervention for high-risk children are recommended. Promoting maternal education, prenatal care, and breastfeeding, alongside improved neonatal monitoring, can help mitigate DD risks
Article Type :
Research |
Subject:
General Received: 2024/11/28 | Accepted: 2025/05/6 | Published: 2026/01/11