Introduction: A group of acute infection diseases are called Relapsing fever.‎ Clinically it involves a circular period of fever and lack of fever. Mortality rate can be ‎decreased by controlling and identifying effective factors.‎

 Objective: This study aimed to determine effective factors for relapsing fever in clients ‎referring to health centers in Khalkhal in ‎‏2002‏‎.

‎ Methods: In this descriptive study, ‎‏59‏‎ clients who had the entrance criteria were selected as ‎sample by census. Data collection was done by interview and observation. Data collection ‎instrument included interview sheet, observation check list and data recording sheet. Content ‎validity was used to determine instrument validity and Retest was used to determine its ‎reliability. SPSS and descriptive-analytic statistics were used for data analysis. ‎ Results: Finding of study indicated the effective environmental factors (Mean=‎‏71.78‏‎), health ‎behaviors (Mean=‎‏84.34‏‎), Socio-economic factors (Mean=‎‏52.12‏‎), cultural (Mean=‎‏91.53‏‎) and ‎finding showed a significant relationship between some personal characteristics and relapsing ‎fever.‎ Conclusion: Relapsing fever in Khalkhal villages was due to tick and effective factors ‎recognized as cultural factors, health behaviors, environmental and Socio-economic factors.‎